You're describing a chemical compound with the systematic name **(5-methyl-3-isoxazolyl)[4-(5-propyl-2-pyrimidinyl)piperazino]methanone**. This name reveals a complex structure:
* **5-methyl-3-isoxazolyl:** This part indicates an isoxazole ring (a five-membered heterocycle containing an oxygen and a nitrogen atom) with a methyl group at the 5th position and an unknown functional group at the 3rd position.
* **[4-(5-propyl-2-pyrimidinyl)piperazino]:** This part signifies a piperazine ring (a six-membered heterocycle containing two nitrogen atoms) with a propyl-substituted pyrimidine ring attached at its 4th position.
* **methanone:** This final part signifies a ketone group (C=O) attached to the isoxazole ring.
This compound is likely a **potential drug candidate** due to its complex structure and the presence of pharmacologically relevant moieties (isoxazole, pyrimidine, and piperazine). It's important to understand that without further information, it's impossible to pinpoint its exact role in research.
**Here's why such compounds are important for research:**
* **Drug Discovery:** The compound may exhibit biological activity against specific targets, making it a potential lead compound for drug development.
* **Chemical Biology:** The compound could be used to study the function of specific biological pathways or proteins.
* **Materials Science:** Some compounds with similar structures may exhibit interesting properties for use in materials development.
**To understand the true significance of this compound, you'd need more context:**
* **Research area:** What field is this compound being investigated in? (e.g., oncology, neurology, etc.)
* **Target:** What biological target is this compound meant to interact with? (e.g., enzyme, receptor, etc.)
* **Activity:** What biological effects does this compound demonstrate? (e.g., inhibition, activation, etc.)
**For further information:**
* You'll need to search for scientific publications or databases that mention this specific compound and its potential applications.
* You can also use online chemical databases like PubChem or ChemSpider to find more information about its structure, properties, and potential activities.
Remember, the name alone tells us very little about the compound's significance. It's crucial to consider the context and the research that has been conducted with it.
ID Source | ID |
---|---|
PubMed CID | 2812702 |
CHEBI ID | 190559 |
Synonym |
---|
OPREA1_665144 |
SR-01000631049-1 |
HMS1663N15 |
(5-methyl-1,2-oxazol-3-yl)-[4-(5-propylpyrimidin-2-yl)piperazin-1-yl]methanone |
(5-methyl-3-isoxazolyl)[4-(5-propyl-2-pyrimidinyl)piperazino]methanone |
CHEBI:190559 |
CCG-40942 |
Class | Description |
---|---|
N-arylpiperazine | |
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Assay ID | Title | Year | Journal | Article |
---|---|---|---|---|
AID588519 | A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities | 2011 | Antiviral research, Sep, Volume: 91, Issue:3 | High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors. |
AID540299 | A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21 | Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. |
AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | 2014 | Journal of biomolecular screening, Jul, Volume: 19, Issue:6 | A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum. |
AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | |||
AID1159607 | Screen for inhibitors of RMI FANCM (MM2) intereaction | 2016 | Journal of biomolecular screening, Jul, Volume: 21, Issue:6 | A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 4 (80.00) | 24.3611 |
2020's | 1 (20.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (13.13) All Compounds (24.57) |
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 5 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |